ライブディーラーおすすめ

fixed#fixed" data-fixed-isfixed-value="false"> Academics Research Campus Life Admissions & Aid About ACCESS Apply GIVE JP EN For Others, With Others shortcut-nav#toggleOpen"> JP EN ACCESS APPLY GIVE Articles Features The Knot Exploring the potential of natural products chemistry #Faculty #Chemistry Division #Master’s & Doctoral Programs in Science and Technology #Department of Materials and Life Sciences #Graduate School of Science and Technology #Faculty of Science and Technology 2023.11.15 Toyonobu Usuki Professor Department of Materials and Life Sciences Faculty of Science and Technology copyurl#copy"> bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Professor Toyonobu Usuki of the Faculty of Science and Technology conducts research on amino acids synthesis and analysis for diagnosing chronic lung disease. Meanwhile, he has techniques for extracting active ingredients from plant waste. Here, he discusses the potential of naturally occurring substances, and the rewarding aspects of engaging in research that benefits society. My research area covers natural products chemistry, a subfield of organic chemistry that encompasses all substances created by organisms, including humans, animals, plants, fish, and microorganisms. One of the molecules I am particularly focused on is “desmosine”, a beautiful amino acid found abundantly in human skin, blood vessels, ligaments, and lungs. Chemical synthesis of desmosine to diagnose lung disease I determined to research desmosine after meeting Professor Gerard M. Turino MD, a key figure in chronic obstructive lung disease (COPD) research, when I was researching at Columbia University in the US. COPD is characterized by shortness of breath and reduced lung functionality due to permanent lung damage, often as a result of long-term smoking. While the number of COPD sufferers is increasing globally, early detection of the disease remains problematic. Professor Turino told me that levels of desmosine, an amino acid found in elastin protein, increase in COPD patients with permanent lung damage—and that this increase could possibly be used for diagnosing COPD. Since the body only generates a minute amount of desmosine, precise measurement requires the use of a synthetic form called an isotopically labelled compound The synthetic compound has the same chemical structure as naturally occurring desmosine, but a different mass. When it is added to urine or blood, it accurately indicates the desmosine content. Professor Turino encouraged me to try creating this isotopically compound, which had yet to be created by anyone anywhere in the world. When I returned to Japan, I commenced with the research at once. After four years, I succeeded in creating the world’s first synthetic desmosine compound; since then, I have also managed to chemically synthesize many related chemical compounds including isotopic desmosine. At present, I am preparing to carry out new research with clinicians and private enterprises aimed at using this synthetic desmosine to diagnose COPD and other diseases characterized by elastin degradation. If you fail, try and try again Another area of my research centers on extracting polyphenols from plants. Polyphenols exert antioxidants and anti-aging properties, which are used in cosmetics and health foods. If we can extract them more efficiently, we should be able to broaden their scope of applications. Using deep eutectic solvents and other special solvents, we have developed methods for extracting polyphenols contained in the leaves of sweet potatoes, and polyphenols contained in “kabuchii”—a type of citrus fruit native to Okinawa. The sweet potato polyphenols have been productized in the form of sweet potato leaf tea; for the kabuchii polyphenols, we have commenced joint research with cosmetics manufacturers with the aim of using them in cosmetics. I begin my research by drawing up a plan of the process from start to goal—perhaps a better way of putting it is that I use existing information to “predict” what will happen as a scientist. Based on this plan, I experiment by mixing different ingredients and reagents in flasks and beakers. However, these experiments never follow the path I predicted—80 percent of my experiments end in failure. It is painstaking, time-consuming work. Yet this is the standard way of carrying out experimental chemistry research—persisting with your experiments, and trying again and again. In my research, I am motivated by a desire to benefit society. I hope that my research into desmosine will contribute to medicine, and that the techniques I have developed for extracting polyphenols from plant waste will contribute to Sustainable Development Goals (SDGs). I am also concurrently working on several other multi-year research projects. Going forward, I will continue devoting myself to research so that I can produce as many beneficial results as possible. The book I recommend “Kokoro” by Soseki Natsume, Kadokawa Bunko I first read Kokoro when I was a high school student. The final part of the story, which comprises a long confessional letter written by “Sensei,” was astonishing. I wish to astound the world with a similarly jaw-dropping narrative arc in my research, too—this is something I think about all the time. Toyonobu Usuki Professor Department of Materials and Life Sciences Faculty of Science and Technology Professor Toyonobu Usuki obtained BS, MS, and PhD from the Department of Chemistry, Tohoku University. After working as a postdoctoral scientist at the Department of Chemistry, Columbia University, he was joined at the Department of Materials and Life Sciences, Sophia University as an assistant professor. He was appointed as a full professor in 2021. Department of Materials and Life Sciences Interviewed: June 2023 copyurl#copy"> bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> #The Knot- Nexus of Knowledge by Sophia Professors #Faculty #Chemistry Division #Master’s & Doctoral Programs in Science and Technology #Department of Materials and Life Sciences #Graduate School of Science and Technology #Faculty of Science and Technology View full article list Related Contents The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Rethinking Education by Treating Everyone as Individuals #Department of Education#Master’s (Doctoral) Program in Education 2023.02.16 Read The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Coffee Farmers in Timor-Leste Make Us Question the Meaning of Wealth #Department of Global Studies#Faculty of Global Studies 2023.02.16 Read The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> When Societies and Political Systems Change, so too do Historical Memories #Department of Liberal Arts#Faculty of Liberal Arts 2023.08.21 Read The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Coloring historical fact with emotion #Department of History#Faculty of Humanities 2023.12.07 Read The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Exploring theatrical works of Early Modern Europe through archival discoveries #Faculty of Humanities#Department of French Literature 2024.03.07 Read The Knot- Nexus of Knowledge by Sophia Professors bookmark#toggle keyup.enter->bookmark#toggle onBookmarkItemUpdate@window->bookmark#handleUpdate"> Decarbonization: Is it really an SDG? Formulating initiatives that will shape the future #Master’s (Doctoral) Program in Global Environmental Studies#Graduate School of Global Environmental Studies 2023.09.07 Read HOME Articles Features The Knot- Nexus of Knowledge by Sophia Professors Exploring the potential of natural products chemistry Sophia University For Others, With Others Official Social Media Academics accordion#toggle" > Undergraduate Programs accordion#toggle" > Faculty of Theology Faculty of Humanities Faculty of Human Sciences Faculty of Law Faculty of Economics Faculty of Foreign Studies Faculty of Global Studies Faculty of Liberal Arts Faculty of Science and Technology SPSF: Sophia Program for Sustainable Futures University-wide General Education accordion#toggle" > Studies in Christian Humanism Embodied Wisdom The Art of Thinking and Expression Data Science Language Education Global Education at Sophia University accordion#toggle" > Learning at Sophia University Learning Abroad Learning Support Graduate Programs accordion#toggle" > Graduate School of Theology Graduate School of Humanities Graduate School of Applied Religious Studies Graduate School of Human Sciences Graduate School of Law Graduate School of Economics Graduate School of Languages and Linguistics Graduate School of Global Studies Graduate School of Science and Technology Graduate School of Global Environmental Studies Graduate Degree Program of Applied Data Sciences Course of Midwifery Lifelong Learning Research accordion#toggle" > Sophia University Research Initiatives accordion#toggle" > Sophia Open Research Weeks (SORW) Research Institutes Industry-Government-Academia Collaboration Intellectual Property Sophia University’s Research Promotion System accordion#toggle" > Research on Priority Areas and Research on Optional Subjects Regulations Governing Research Activities and Use of Research Funds Campus Life accordion#toggle" > Semester Classification and Class Schedule Extracurricular Activities Volunteer Activities Global Learning Community Student Counseling Services accordion#toggle" > Mental and Physical Health Consultation Harassment Prevention Measures Support for Students with Disabilities Career Development Support accordion#toggle" > Career Design Program Career support for students with Study Abroad experience / Global Careers Statistics Relating to Post-graduation Employment (Provisional Acceptance), Graduate Outcomes, etc. Guidance for Corporate Recruiters Guidance for Graduates Housing Support Facilities Available on and off Campus accordion#toggle" > Facilities available at the Yotsuya Campus Other Facilities Admissions & Aid accordion#toggle" > Sophia University Admissions Policy Degrees offered by Sophia University Non-Matriculated Student Research Student, Foreign Special Research Student, and MEXT Scholarship Student Exchange Student from an Overseas University Non-Degree Student Sophia Short-term Program Student Tuition and Scholarships accordion#toggle" > Tuition Scholarships to Apply for Before Entering Undergraduate Programs Scholarships for Undergraduate Students New National Financial Support Program for Receiving Higher Education Scholarships for Graduate School Students Expenses and Scholarships for Studying Abroad Financial Support for Those with Abrupt Changes in Family Economic Circumstances and for Victims of Disasters About accordion#toggle" > Message from the President The Spirit of Sophia University accordion#toggle" > Philosophy of Sophia University History of Sophia University Sophia Archives Sophia as a Catholic University Global Engagement accordion#toggle" > Visits from Global Intellectuals Global Campus United Nation Weeks &＃038; Africa Weeks SDGs & Sustainability Initiatives Initiatives to Promote Diversity Sophia School Corporation Facts & Figures Sophia University&＃8217;s Network accordion#toggle" > Network with Alumni Network with Parents and Guarantors Networking with the Community Domestic & International Networks Sophia University&＃8217;s Publications accordion#toggle" > University Brochure/ Graduate School Brochure SOPHIA magazine Sophia University Press Sophia University&＃8217;s Visual Identity and School Anthem accordion#toggle" > Sophia University Visual Identity Official Character “Sophian-kun” Virtual Backgrounds School Anthem / Student Song Media Relations and Filming/Photograpy on Campus Sophia University Campus and Overseas Offices accordion#toggle" > Campus Overseas Offices Support from the SOPHIA Fund for the Future Teaching Collaboration Initiatives Privacy Policy For Prospective Students For Guarantors For Current Students, Faculty and Staff For Alumni For General Public For Corporate Partners, Press and Media Official Social Media Sophia School Corporation Sophia University Sophia University Junior College Division Eiko Gakuen Junior and Senior High School Rokko Junior and Senior High School Hiroshima Gakuin Junior and Senior High School Sophia Fukuoka Junior and Senior High School Contact Us Site Map Website Policy Employment For Others, With Others © Sophia University. All Rights Reserved. Page top drawer#toggle" data-drawer-target="trigger" data-drawer-trigger-param="search" > drawer#toggle" data-drawer-target="trigger" data-drawer-trigger-param="menu" > ACCESS Apply GIVE JP EN For Others, With Others ACCESS JP EN Apply GIVE Academics accordion#toggle" > Undergraduate Programs accordion#toggle" > Faculty of Theology Faculty of Humanities Faculty of Human Sciences Faculty of Law Faculty of Economics Faculty of Foreign Studies Faculty of Global Studies Faculty of Liberal Arts Faculty of Science and Technology SPSF: Sophia Program for Sustainable Futures University-wide General Education accordion#toggle" > Studies in Christian Humanism Embodied Wisdom The Art of Thinking and Expression Data Science Language Education Global Education at Sophia University accordion#toggle" > Learning at Sophia University Learning Abroad Learning Support Graduate Programs accordion#toggle" > Graduate School of Theology Graduate School of Humanities Graduate School of Applied Religious Studies Graduate School of Human Sciences Graduate School of Law Graduate School of Economics Graduate School of Languages and Linguistics Graduate School of Global Studies Graduate School of Science and Technology Graduate School of Global Environmental Studies Graduate Degree Program of Applied Data Sciences Course of Midwifery Lifelong Learning Research accordion#toggle" > Sophia University Research Initiatives accordion#toggle" > Sophia Open Research Weeks (SORW) Research Institutes Industry-Government-Academia Collaboration Intellectual Property Sophia University’s Research Promotion System accordion#toggle" > Research on Priority Areas and Research on Optional Subjects Regulations Governing Research Activities and Use of Research Funds Campus Life accordion#toggle" > Semester Classification and Class Schedule Extracurricular Activities Volunteer Activities Global Learning Community Student Counseling Services accordion#toggle" > Mental and Physical Health Consultation Harassment Prevention Measures Support for Students with Disabilities Career Development Support accordion#toggle" > Career Design Program Career support for students with Study Abroad experience / Global Careers Statistics Relating to Post-graduation Employment (Provisional Acceptance), Graduate Outcomes, etc. Guidance for Corporate Recruiters Guidance for Graduates Housing Support Facilities Available on and off Campus accordion#toggle" > Facilities available at the Yotsuya Campus Other Facilities Admissions & Aid accordion#toggle" > Sophia University Admissions Policy Degrees offered by Sophia University Non-Matriculated Student Research Student, Foreign Special Research Student, and MEXT Scholarship Student Exchange Student from an Overseas University Non-Degree Student Sophia Short-term Program Student Tuition and Scholarships accordion#toggle" > Tuition Scholarships to Apply for Before Entering Undergraduate Programs Scholarships for Undergraduate Students New National Financial Support Program for Receiving Higher Education Scholarships for Graduate School Students Expenses and Scholarships for Studying Abroad Financial Support for Those with Abrupt Changes in Family Economic Circumstances and for Victims of Disasters About accordion#toggle" > Message from the President The Spirit of Sophia University accordion#toggle" > Philosophy of Sophia University History of Sophia University Sophia Archives Sophia as a Catholic University Global Engagement accordion#toggle" > Visits from Global Intellectuals Global Campus United Nation Weeks &＃038; Africa Weeks SDGs & Sustainability Initiatives Initiatives to Promote Diversity Sophia School Corporation Facts & Figures Sophia University&＃8217;s Network accordion#toggle" > Network with Alumni Network with Parents and Guarantors Networking with the Community Domestic & International Networks Sophia University&＃8217;s Publications accordion#toggle" > University Brochure/ Graduate School Brochure SOPHIA magazine Sophia University Press Sophia University&＃8217;s Visual Identity and School Anthem accordion#toggle" > Sophia University Visual Identity Official Character “Sophian-kun” Virtual Backgrounds School Anthem / Student Song Media Relations and Filming/Photograpy on Campus Sophia University Campus and Overseas Offices accordion#toggle" > Campus Overseas Offices Support from the SOPHIA Fund for the Future Teaching Collaboration Initiatives Privacy Policy Official Social Media Frequently Viewed Pages Sophia University Campus and Overseas Offices Facts & Figures The Spirit of Sophia University English-taught Programs For Prospective Students For Guarantors For Current Students, Faculty and Staff For Alumni For General Public For Corporate Partners, Press and Media Sophia School Corporation Sophia University Sophia University Junior College Division Eiko Gakuen Junior and Senior High School Rokko Junior and Senior High School Hiroshima Gakuin Junior and Senior High School Sophia Fukuoka Junior and Senior High School Contact Us Site Map Website Policy Employment © Sophia University. All Rights Reserved. ACCESS Apply GIVE JP EN For Others, With Others Frequently Searched Keywords Faculty Scholarship Open Campuses Study Abroad Programs Extracurricular Activities We use COOKIEs on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the COOKIEs. However, you may visit "COOKIE Settings" to provide a controlled consent. View COOKIE policy COOKIE Settings Accept All Manage consent Close Privacy Overview This website uses COOKIEs to improve your experience while you navigate through the website. Out of these, the COOKIEs that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party COOKIEs that help us analyze and understand how you use this website. These COOKIEs will be stored in your browser only with your consent. You also have the option to opt-out of these COOKIEs. But opting out of some of these COOKIEs may affect your browsing experience. Analytics Analytics Analytical COOKIEs are used to understand how visitors interact with the website. These COOKIEs help provide information on metrics the number of visitors, bounce rate, traffic source, etc. SAVE & ACCEPT